The 4 pillars of longevity: how to prevent ageing and heal with Dr Darshan Shah

Date: 2025-08-13 11:00:23

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📌 Biomarkers guide: https://www.drshah.com/biomarkers

If you want to know how to live longer, prevent ageing, and stay healthy after 40, this episode is for you. I’m sitting down with longevity medicine specialist Dr Darshan Shah to talk about the 4 pillars of longevity, sharing practical, evidence-based steps to improve your healthspan, reduce your risk of disease, and maintain your energy as you age.

Longevity is exploding in popularity. On my recent trip to LA it was clear that biohacking has evolved into a genuine branch of medicine, now practised by leading medical researchers and doctors. One of the people at the forefront is Dr Darshan Shah, a board-certified surgeon who has performed over 20,000 surgical operations, including trauma and complex reconstructive procedures. As a specialist in longevity medicine, he has helped thousands of patients improve their health, extend their healthspan and increase their lifespan.

Dr Shah earned his medical degree at just 21, becoming one of the youngest doctors in the United States. He trained at the Mayo Clinic, has authored numerous papers, patented medical devices, and continued his education at Harvard Business School, Singularity University and other prestigious institutions.

In this episode, I sat down with Dr Shah at one of his Next Health Clinic branches in West Hollywood to explore the 4 pillars of longevity:
• Lifestyle medicine – diet, sleep and exercise
• Functional medicine – detoxification, emotional health, hormones and inflammation
• Preventive medicine – screening for heart health, brain health and cancer
• Longevity medicine – peptides, supplements, IVs and more

📌 Key chapters
00:00 – The four pillars of healthy ageing
03:51 – Deprocessing your diet
04:33 – The best workout after 40
05:38 – How to improve sleep after 40
10:06 – How often to strength train after 40
14:12 – Breaking through workout plateaus
16:16 – Functional medicine explained
17:43 – Hormone health
25:21 – How to detoxify your life
28:33 – Clean air at home
29:31 – What is reverse osmosis water
32:15 – Reducing toxins in food and skincare
37:14 – Why emotional health matters after 40
42:08 – Preventive medicine after 40
44:33 – Brain health screening
46:15 – Colonoscopy frequency after 40
47:23 – Annual home stool testing
48:55 – How to check your skin for cancer
49:28 – The Clearly scan for heart health
52:16 – Longevity medicine explained
54:51 – Peptides and advanced supplements
55:42 – Which magnesium should you take
56:41 – The benefits of creatine for over 40s

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